When should you use a hyphen in a prefix?

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When should you use a hyphen in a prefix?

A hyphen should be used in a prefix when it is attached to a proper noun or a number, or when it is necessary to avoid confusion or misinterpretation. Additionally, a hyphen should be used when the prefix is attached to a word that starts with the same letter, or when it is used to join two words that would otherwise be written separately.