What are the major databases used in bioinformatics?

Bioinformatics Questions



80 Short 76 Medium 47 Long Answer Questions Question Index

What are the major databases used in bioinformatics?

Some of the major databases used in bioinformatics include:

1. GenBank: It is a comprehensive database maintained by the National Center for Biotechnology Information (NCBI) that contains DNA sequences from various organisms.

2. Protein Data Bank (PDB): It is a repository of 3D structural data of proteins and nucleic acids. It provides information on the structure, function, and interactions of biomolecules.

3. UniProt: It is a comprehensive resource that provides information on protein sequences, functions, and annotations. It integrates data from various sources and is widely used for protein research.

4. Ensembl: It is a genome annotation database that provides information on genes, transcripts, and proteins of various organisms. It also includes comparative genomics data and functional annotations.

5. Kyoto Encyclopedia of Genes and Genomes (KEGG): It is a database that provides information on biological pathways, diseases, and drugs. It integrates genomic, chemical, and systemic functional information.

6. NCBI Gene: It is a database that provides information on genes, including their sequences, functions, and associated diseases. It also includes data on gene expression and genetic variations.

7. Reactome: It is a database that provides information on biological pathways and their interactions. It includes detailed pathway diagrams and annotations.

These databases play a crucial role in storing, organizing, and retrieving biological data, enabling researchers to analyze and interpret complex biological information.