Bioinformatics Questions
Epigenomics in bioinformatics refers to the study of epigenetic modifications on a genome-wide scale. Epigenetics refers to changes in gene expression or cellular phenotype that do not involve alterations in the DNA sequence itself. These modifications can include DNA methylation, histone modifications, and non-coding RNA molecules. Epigenomics aims to understand how these modifications regulate gene expression and cellular function, and how they can be influenced by environmental factors. Bioinformatics plays a crucial role in epigenomics by developing computational tools and algorithms to analyze and interpret large-scale epigenetic data, such as DNA methylation patterns or histone modification profiles. These analyses help in identifying epigenetic markers associated with diseases, understanding the mechanisms underlying gene regulation, and potentially developing epigenetic-based therapies.